Excipients for Oral & TopicalJPUSP/NFPh. Eur.

Low-Substituted Hydroxypropyl Cellulose (L-HPC LH-11, LH-21, LH-22)

Water-insoluble swellable cellulose superdisintegrant & dry binder

Low-Substituted Hydroxypropyl Cellulose (L-HPC LH-11, LH-21, LH-22) is a water-insoluble swellable superdisintegrant and dry binder for direct compression.

infoProduct Description

Low-Substituted Hydroxypropyl Cellulose (L-HPC) LH-11, LH-21, and LH-22 is a pharmaceutical-grade, partially substituted cellulose ether. Unlike conventional HPC, L-HPC is insoluble in water but rapidly swells upon contact with aqueous media, making it an outstanding tablet disintegrant and dry binder.

starsKey Features & Advantages

  • task_altWater-insoluble partially substituted cellulose polymer
  • task_altRapidly swells in water promoting fast tablet disintegration & release
  • task_altActs as an effective dry binder, enhancing tablet hardness
  • task_altSuitable for direct compression and wet granulation
  • task_altLow hygroscopicity maintaining formulation stability
  • task_altAvailable in LH-11, LH-21, and LH-22 grades for particle size optimization
  • task_altComplies with JP and major pharmacopeias

sciencePharmaceutical Applications

verifiedDirect Compression Tablet Disintegration
verifiedImmediate Release Tablets

fact_checkKey Specifications

Grades Available
LH-11, LH-21, LH-22
Action
Rapid Swelling Disintegration

verifiedQuality Assurance

Global GMP Compliant & Pharmacopeia Grade

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