Excipients for Oral & TopicalUSP/NFPh. Eur.JP
D-Mannitol
Non-hygroscopic sugar alcohol for chewable tablets & ODTs
D-Mannitol is a non-hygroscopic polyol sugar alcohol providing a pleasant cooling taste, excellent flowability, and compressibility for chewable tablets, ODTs, and topical gels.
infoProduct Description
D-Mannitol is a widely used pharmaceutical excipient that functions as a diluent, filler, bulking agent, sweetener, and tonicity-adjusting agent in oral and topical formulations. It is a white, crystalline, non-hygroscopic sugar alcohol with excellent chemical stability.
starsKey Features & Advantages
- task_altWhite, odorless, crystalline powder with a mildly sweet taste
- task_altNon-hygroscopic, ensuring excellent stability in moisture-sensitive formulations
- task_altChemically inert and compatible with a wide range of APIs and excipients
- task_altServes as an effective diluent and filler in tablets and capsules
- task_altProvides a pleasant cooling sensation, making it ideal for chewable tablets and lozenges
- task_altSuitable for direct compression because of its good flowability and compressibility
- task_altLow glycemic index and non-cariogenic, making it suitable for sugar-free formulations
- task_altUsed as a bulking agent in oral solid dosage forms
- task_altFunctions as a tonicity-adjusting agent in certain pharmaceutical preparations
- task_altIn topical formulations, acts as a humectant, stabilizer, and viscosity modifier
- task_altHigh chemical and physical stability, resulting in a long shelf life
- task_altAvailable in multiple particle-size grades
- task_altAccepted by USP-NF, Ph. Eur., and JP
sciencePharmaceutical Applications
verifiedChewable Tablets & ODTs
verifiedLozenges & Sugar-Free Tablets
verifiedTopical Gels
fact_checkKey Specifications
Taste & Odor
Odorless with mildly sweet cooling taste
Hygroscopicity
Non-hygroscopic
verifiedQuality Assurance
Global GMP Compliant & Pharmacopeia Grade